Penile dermatoglyphs are rare and are a type of generalized dermatoglyphs. Generalized dermatoglyphs occur in the hair, neck, forehead and extremities and are associated with sweat hole keratosis disorder, hair follicles, genetics and other factors. It is generally believed that penile corns are formed by continued keratinization on the basis of warts or echinoderma, which can occur at any age and are more common in adults after marriage. The cause of the disease is unknown, and it is speculated that it may be related to local chronic inflammation caused by circumcision, prepuce, poor hygiene, acromegaly, viral infection, etc. Penile skin horns are mostly located at the coronal sulcus of the penis head, which is an abnormal accumulation of skin keratin layer confined to a certain area, with yellow surface rough horns, which can reach several centimeters in size. Since penile corns are precancerous and have a malignant rate of 33%-37%, and the effect of topical medication is poor, they should be removed surgically at an early stage. For larger penile cortex and older patients, partial penile excision can be chosen; for younger patients, complete local excision is preferred to preserve the penis and maintain sexual function, with close postoperative follow-up to prevent recurrence and malignant change.