The clinical manifestations of typical typhoid fever are: 1, fever, body temperature can be as high as 39-40 ℃, if not timely use of antibiotics, fever can last for about two weeks, accompanied by systemic symptoms, such as headache, fatigue, loss of appetite, sore throat, cough, but also diarrhea, constipation, abdominal distension and other gastrointestinal symptoms; 2, rash, about half of the patients can appear rose rash, mainly distributed in the chest and abdomen, back of the shoulder, in the form of 3, relatively slow pulse; 4, hepatosplenomegaly; 5, neurological symptoms, such as indifference, unresponsiveness, hearing loss, agitation, delirium, and in severe cases, coma; 6, complications, the most common complications of typhoid fever are intestinal bleeding and intestinal perforation.