When doing the new coronavirus nucleic acid test, the test can be done through the nasal passages. The new coronavirus is mainly a respiratory viral infection, and the virus is mainly found in the respiratory tract, so it can be detected by two methods: nasopharyngeal swab and oropharyngeal swab. Because the nasal and posterior pharyngeal walls have more secretions, the viral content will be higher, and it is also the place where the novel coronavirus infection starts. Usually, the viral infection enters the body through the nasal or oropharyngeal region, so it is necessary to collect a specimen from that area, and the specimen will be subjected to a nucleic acid test for the infection of the novel coronavirus. Nasopharyngeal swabs are taken by gently and slowly extending the swab through the nose to the nasopharynx, leaving it for a few seconds to aspirate the secretions for nucleic acid testing, which is a more accurate method of testing and is also easier to collect. However, some people may experience itchy nose or sneezing after collection, or a small amount of bleeding from the nose, which generally does not require special treatment. In addition to nasopharyngeal swabs and oropharyngeal swabs, anal swabs can also be applied clinically to clarify the presence of novel coronavirus infection in the examinee. Therefore, people should pay attention to good personal protection in daily life and need to wear masks when going out.