Possible causes of bilateral toe sensation abnormalities include peripheral neuropathy, sciatic nerve injury, and herniated intervertebral disc compressing the nerves. 1. Peripheral neuropathy: the causes of peripheral neuropathy are more complicated, including drug poisoning, infection, tumor, immune abnormalities and so on. These factors may lead to abnormal conduction of peripheral nerves, resulting in numbness, sensitivity and other abnormal sensory symptoms. 2. Sciatic nerve injury: the main causes of sciatic nerve injury include trauma to the back of the thigh and buttocks, drug injection injury, etc. After sciatic nerve injury, pressure pain, numbness, distension and other discomforts are usually seen locally in the lower limbs. 3. Herniated disc compressing the nerve: Herniated disc compressing the nerves of the surrounding tissues usually results in abnormal sensation in the lower limbs, which can be manifested as numbness, weakness, and so on. Bilateral toe sensory abnormalities, it is recommended to go to the regular hospital in a timely manner to find out the cause and actively treat.