For patients with hypertension, taking reserpine has no obvious benefits for the body. 3. Long-term application of reserpine can lead to gastric ulcers, especially for patients with chronic gastric disease, it is not advisable to take reserpine in large quantities or for a long period of time, as it has obvious stimulating symptoms for the digestive system, accompanied by nausea, vomiting, diarrhea, etc. 4. The side effects of long-term use of reserpine on the cardiovascular system may include arrhythmias.