Irbesartan generally refers to Irbesartan tablets, Betalucel generally refers to metoprolol tartrate tablets, the two can generally be taken together, but patients need to strictly comply with the doctor’s instructions to avoid unauthorized co-taking of the above drugs. Irbesartan tablets are common clinical drugs, belonging to the angiotensin II receptor antagonist, mainly used in the treatment of essential hypertension, at the same time can be used in the treatment of hypertension combined with type 2 diabetic nephropathy. The drug’s blood pressure lowering effect is relatively good, at the same time, clinical research found that the drug and other β-blockers, calcium channel blockers and other antihypertensive drugs with higher safety, and can enhance the effect of blood pressure lowering. However, it is forbidden for those who are allergic to this product, and patients may experience adverse reactions such as headache, dizziness, palpitations, etc. after using the drug, and a few patients may manifest cough, urticaria, angioneurotic edema, etc., which are generally mild and transient. Metoprolol tartrate tablets is a kind of beta-blocker, clinical mainly used in the treatment of hypertension, arrhythmia, angina pectoris, acute myocardial infarction and other diseases, but for cardiogenic shock, significant bradycardia, severe and remembered heart failure and other patients are prohibited. And some patients may also experience adverse reactions such as decreased blood pressure, conduction block, and slowed heart rate after taking the drug. Since the combination of Irbesartan and beta-blockers can enhance the blood pressure-lowering effect, the above two drugs can generally be taken together for patients with severe hypertension. However, because the two drugs are prescription drugs, patients need to strictly follow the doctor’s instructions, unauthorized use of the same may cause drug interactions, in the non-physician guidance patients should avoid unauthorized combination of drugs.