Gallbladder stones are most often found after ultrasonography, and can cause stone cholecystitis when they block the gallbladder and damage the mucosa, so it is possible to see the two episodes half a month apart. The causes of gallbladder stones are complex, and can be related to factors such as causing bile stasis and affecting the ratio of cholesterol and bile acid-phospholipid concentration, etc. Most of the patients are asymptomatic, but there can be biliary colic, acute or chronic cholecystitis and other manifestations. When gallbladder stones move to block the gallbladder duct or embedded in the neck of the gallbladder, it can directly damage the mucous membrane of the gallbladder in the pressurized area, obstructing the discharge of bile, causing edema and necrosis of the gallbladder, that is, stone cholecystitis occurs. Cholecystitis acute attack of epigastric pain, accompanied by nausea, vomiting and other digestive symptoms, the development of the disease can cause gangrene, perforation of the gallbladder and other serious consequences, it is recommended that timely medical treatment, the cause of the symptomatic treatment.