Whether or not to use medication for high neutrophil percentage needs to depend on the specific cause of the disease, it can be treated without medication, or antibiotics, chemotherapeutic drugs, targeted drugs, immunosuppressants, etc. can be used. The specific use of which drugs need to be selected according to the specific cause of the disease. The causes of high neutrophil percentage include physiological increase, bacterial infection, tumor and so on. 1. Physiological increase: strenuous exercise, satiety, high temperature environment will cause neutrophil elevation, in addition, there is no other abnormal performance or discomfort, this situation does not require the use of drugs. 2. Bacterial infections: such as staphylococcus aureus, streptococcus infections can cause neutrophil percentage increase, according to the type of bacterial infection, choose the appropriate antibiotics, such as penicillin, erythromycin, azithromycin and so on. 3. Tumor: Tumor diseases such as leukemia can also cause increased neutrophil percentage, according to the specific tumor diseases, chemotherapy drugs such as paclitaxel, vincristine, cisplatin, etc., targeted drugs such as bevacizumab, gefitinib, erlotinib, etc., immunosuppressant drugs such as cyclophosphamide. Neutrophil percentage increase may also have other reasons, such as allergies, etc. It is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.