There are many causes of blisters on the feet, such as local friction, eczema, tinea pedis, etc. The specific treatment needs to be chosen according to the condition. 1. local friction: wearing shoes that do not fit the feet, walking frequent friction can be caused by blisters, need to replace loose and comfortable shoes and socks, blisters larger can go to the hospital with a sterile syringe to draw out the blisters, local disinfection treatment. 2. eczema: you can choose to use glycerite lotion, boric acid, zinc oxide, ice ointment and other medications under the guidance of a professional doctor to astringent, promote the local dryness, to be free of obvious blisters, oozing, topical hydrocortisone butyrate cream, tretinoin cream and other medications, itching is significant can be orally loratadine tablets, cetirizine hydrochloride tablets, and other medications for the treatment. 3. Tinea pedis: when there are blisters, you should choose the creams or aqueous agents (such as azole creams or solutions, etc.) with little irritation, and then use terbinafine hydrochloride cream, naftifine ketoconazole cream and other medications externally after there are no obvious blisters for treatment. Causes of blisters on the feet more causes, should also go to the hospital in time for examination and diagnosis, under the guidance of professional doctors to use drugs.