Vulvar leukoplakia, also known as vulvar dystrophy, is mainly caused by the degeneration of the vulvar skin, but if it continues to develop, it may lead to cancer. Once the biopsy confirms the diagnosis of cancerous vulvar leukoplakia, it is necessary to be hospitalized and complete the preoperative examination. If there are no contraindications, general anesthesia surgery is required to completely excise the cancerous part of the vulva, and it is necessary to expand the scope of the excision surgery. After the surgery, corresponding radiotherapy is also needed, usually the use of paclitaxel, cisplatin or carboplatin can be considered for chemotherapy, which usually requires about 6 courses of treatment.