There are many small holes on the soles of the feet like a beehive, consider the possibility of fossa keratolysis, but also may be blistering tinea pedis and other diseases. 1. Fossa keratolytica: Fossa keratolytica is a bacterial skin infection of the foot, such as foot sweating, etc., easily induced bacterial infections, which can lead to the disease; diabetes can lead to foot ulcers and infections, which may be secondary to the disease, so that the palms of the feet, toes, the skin crater-like depressions or a single small pits, accompanied by keratolysis and so on. 2. Blister-type tinea pedis: blister-type tinea pedis is a type of tinea pedis, caused by fungal infection, the main damage is blisters, the blister wall is thicker, blisters can be desquamated after drying up, from the appearance of the soles of the feet there may be a lot of small holes, like a beehive. At the same time there are many small holes in the soles of the feet like a beehive may also be contact dermatitis and other allergic diseases, often caused by contact with allergens, contact dermatitis can appear erythema, papules, if the blisters are gradually absorbed or ruptured, can be formed in the soles of the feet of the beehive-like small holes. It is recommended that patients with honeycomb holes on the soles of their feet go to the dermatology department of a regular hospital in a timely manner to clarify the cause and give appropriate medication.