Colorectal melanosis, clinically known as colorectal melanosis, is a benign and reversible mucosal pigmentation lesion. The causes of colorectal melanosis often include long-term constipation, prolonged use of anthraquinones, inflammatory bowel disease, and so on, and its treatment needs to be based on different causes.
1. Long-term constipation: under long-term constipation, the intestinal tract absorbs melanin particles produced by bacteria, which leads to colorectal melanosis. The treatment should relieve constipation, if it is functional constipation, it should eat more vegetables, fruits and other crude fiber food, and drink more water and exercise; if it is constipation caused by intestinal problems, such as anterior rectal protrusion, puborectalis syndrome, etc. it should be taken to treat the original disease.
2. Prolonged use of anthraquinones: Prolonged use of anthraquinone laxatives is the main cause of colonic melanosis. Anthraquinone laxatives often contain senna, rhubarb and other ingredients, they will destroy the epithelial cells of the small intestine, the epithelial cells are phagocytosed by macrophages to form lipofuscin, causing the darkening of the colon.
Treatment should be taken to stop the use of anthraquinone laxatives, the use of pro-intestinal power drugs, such as domperidone, cisapride and other drugs to promote intestinal peristalsis, which is conducive to defecation; laxative laxative with non-anthraquinone laxatives, such as lactulose, polyethylene glycol dispersal, and other drugs laxative laxative.
3. Inflammatory bowel disease: Inflammatory bowel disease such as Crohn’s disease and ulcerative colitis may also lead to colonic nigrostenosis, and this category of disease mainly adopts close follow-up and treatment of the original disease.
If there is a case of colonic black change disease, should promptly go to the regular hospital, do not self-medication, so as not to cause irreversible damage.