Infants with yellow runny noses should not be vaccinated, try to wait until there is no abnormal discomfort in the body before vaccination. Infants running yellow nose may be a symptom of respiratory tract infection, the baby respiratory tract infection when the body’s immune function will be affected by some of the immune function is in a low state, temporarily should not be vaccinated. Vaccines are generally live attenuated vaccines, if the infant in the case of physical discomfort hit the vaccine, the vaccine inoculated into the body, so that the body’s immune system to produce specific antibodies, to achieve the role of the protection of the body, at this time the baby’s immunity is low, may aggravate the symptoms of respiratory infections, runny nose, but also prone to induce the vaccine’s adverse reactions. Vaccination is to inoculate a small amount of virus into the infant’s body, at this time the infant’s body immunity is relatively poor, it is easy to make the inoculated vaccine virus spread, thus causing the disease. To summarize, infants should wait until there is no abnormality in all aspects of their body before going for vaccination to minimize the impact.