Warfarin is an anti-platelet coagulation drug, which is very effective for the treatment of atrial fibrillation and prevention of blood clots, but long-term consumption of warfarin may cause a variety of hazards to the body: 1. Bleeding: long-term use of warfarin is likely to cause bleeding in various organs, with gastrointestinal bleeding being the most common. Early on, gum bleeding caused by brushing teeth may occur, and bleeding will not stop after wound bleeding. Secondly, the whole body petechiae, petechiae as the performance; 2, liver damage: liver is responsible for drug metabolism and elimination of the main organs, in the process of taking warfarin, will cause toxic damage to the liver or cause liver allergic reactions; 3, osteoporosis: warfarin can significantly inhibit the deposition of extracellular matrix osteocalcin in human bone cells, long-term use of warfarin will lead to osteoporosis, the incidence of fragility fractures significantly increased. Therefore, before taking warfarin, take it under the guidance of a professional physician, follow medical advice, do not casually change the dose, and go to the hospital promptly for any uncomfortable symptoms to avoid delays.