Antibiotics and painkillers can usually be taken 2-3 hours after the extraction under the doctor’s supervision to reduce the post-operative pain and to avoid the appearance of infection. This is because by this time the anesthetic may have worn off and the patient will obviously feel pain at the incision. Antibiotic drugs can choose oral penicillin or cephalosporin. If the wisdom teeth are extracted, they may have to be cut and de-boned and sutured during the extraction process, which is more traumatic. In this case, patients should take anti-anaerobic antibiotics such as Metronidazole and Ornidazole under the guidance of the doctor, to help prevent and reduce the swelling and pain caused by the infection. Painkillers can choose diclofenac sodium extended-release tablets, celecoxib, ibuprofen and so on. Care should be taken when taking medication after an extraction; do not take the medication with water that is too hot, as this may cause the extraction site to bleed again. The blood clot in the alveolar socket is extremely important for wound healing. Drinking water or rinsing your mouth for a non-specified period of time can easily lead to the dissolution and dislodgement of the blood clot, which will increase the risk of secondary infection of the extraction wound or may induce the occurrence of dry socket syndrome.