Antibiotics and painkillers can usually be taken under doctor’s supervision 2-3 hours after tooth extraction to reduce post-operative pain and avoid infection. At this time the anesthesia may have worn off and the patient will obviously feel pain at the incision. Antibiotic medications can be oral cephalosporins, or amoxicillin if you are not allergic. If the wisdom teeth are extracted, they may have to be cut and debrided and sutured during the extraction process, which is more traumatizing, and the patient should take a combination of metronidazole, ornidazole and other anti-anaerobic antibiotics under the guidance of the doctor to help prevent and reduce the swelling and pain caused by the infection. Painkillers can choose diclofenac sodium extended-release tablets, celecoxib, ibuprofen and so on. Be careful when taking medication after an extraction; do not take the medication with water that is too hot, as this may cause the extraction site to bleed again. The blood clot in the alveolar socket is extremely important for wound healing. Drinking water or rinsing your mouth for a non-specified period of time can easily lead to the dissolution and dislodgement of the blood clot, thus increasing the possibility of secondary infection or dry socket in the extraction wound.