DPT vaccine and polio vaccine can be given at the same time, but different injection sites should be chosen. Simultaneous vaccination will not affect the effectiveness of the vaccines or cause side effects. However, a very small number of children may have adverse reactions and should be observed. Because the DPT vaccine is mainly for tetanus disease, while the polio vaccine is mainly for poliovirus infection, it usually does not cause side effects. However, a very small number of children may have an allergic reaction to the vaccine, with an allergic rash on the skin and small hard nodules, redness, swelling or pain at the injection site. After DPT vaccination, children may have fever, irritability and loss of appetite. The fever will not be too high, about 38 degrees, and these adverse reactions will disappear after 1-2 days. If the fever exceeds 38.5 degrees, or the adverse reactions persist, they should go to the hospital promptly and be treated under the advice of a doctor.