Rotundin can be used to relieve headache, mainly has the effect of analgesic, antitussive, hypnotic and so on. Rotundin is a non-narcotic analgesic, adapted to the gastrointestinal tract and the liver and biliary system diseases caused by pain, menstrual pain, post-delivery pain, mild traumatic and post-surgical pain, headache insomnia and spasmodic cough, as well as various causes of cardiac arrhythmia. Rotundin has analgesic, antitussive and hypnotic effects, which begin to take effect 10-30 minutes after taking the drug and can last for 2-5 hours. For the gastrointestinal system of dull pain analgesic effect is better, the effect of trauma pain is poor. For headache insomnia, especially pain-induced insomnia has a better effect. There may be drowsiness, vertigo, fatigue, nausea and so on. Large doses have inhibitory effect on the respiratory center, sometimes can cause extrapyramidal symptoms. It should be noted that if there is a long-term headache, should actively seek medical treatment to find the cause of the disease and treatment, do not take long-term oral analgesic drugs, in order to avoid aggravation of the condition, resulting in adverse consequences.