Anal fissure rubbing medicine, mainly choose some ointment to apply or suppository to improve symptoms and promote healing. Commonly used drugs are local anesthetic drugs, hemorrhoidal ointment, etc. If there is secondary infection, you can rub antibiotic ointment. Anal fissure is a small ulcer formed after cracking the skin layer of the anal canal under the dentate line, which is pike-shaped or oval and causes severe pain around the anus. 1. local anesthetic drugs: you can use topical bupivacaine gel, oxybupivacaine gel, etc., applied to the affected area, can reduce local pain. 2. Hemorrhoidal ointment: Topical hemorrhoidal ointment has the effect of dilating blood vessels and improving circulation, which can also effectively improve the symptoms. 3. Antibiotic ointment: If there is a secondary bacterial infection, you can apply erythromycin ointment, fusidic acid cream and other antibiotic drugs to treat. You can also use 1:5000 potassium permanganate solution for sitz bath wet compress, to achieve the purpose of local anti-inflammatory. Anal fissure patients are recommended to go to the hospital for examination first, under the guidance of the doctor to choose medication, usually should keep the bowel movement, to prevent constipation, there is a need to take anal fissure resection, anal sphincter cut off and other treatment measures.