Coughing with yellow and lumpy sputum is considered to be a combination of bacterial infection, and oral cephalosporins, macrolides or respiratory quinolones antibiotics can be taken. If the cough is lumpy, the sputum is sticky and difficult to be coughed up. In this case, you can take oral phlegmolytic drugs, such as tranylcypromine, acetylcysteine granules and carboxymethylstilbestrol tablets to help dilute the sputum and promote its discharge. In addition, coughing with yellow phlegm is considered to be caused by wind-heat or lung-heat in Chinese medicine, so you can use Chinese medicine to clear the lung and resolve phlegm and stop coughing.