Left frontal lacunar infarction is a small vascular lesion, supplying the deep penetrating branch arteries of the frontal lobe. Because of the formation of small infarct foci after atherosclerotic occlusion, the lesions are all about 2-15 mm in extent and are very mild in symptoms. Patients may exhibit psychiatric symptoms, such as showing emotional indifference, slightly slow reaction, inattentiveness, and patients have decreased judgment and disorientation. Other patients may exhibit clumsy or non-fluent verbal expressions and difficulty finding words. Some patients may also present with mild paralysis of the limbs, which may manifest as monoparesis of the contralateral limb or central facial and tongue paralysis. The treatment for left frontal lobe lacunar cerebral infarction depends on the patient’s consultation time, and can be treated with thrombolysis, antiplatelet aggregation, and fibrinogenesis, while giving the patient to promote neurological recovery.