Hepatitis C generally refers to viral hepatitis C, and only a small number of patients with thirty years of viral hepatitis C can be cured, and most patients may develop cirrhosis of the liver and so on, and even life-threatening. Early standardized treatment for patients with viral hepatitis C can achieve clinical cure, but most of the thirty years of viral hepatitis C is more serious, only a small number of patients can be cured after standardized and effective treatment. However, most patients will gradually deteriorate and even develop cirrhosis if they do not receive timely treatment. Patients at this stage, are prone to ascites, bleeding from esophagogastric varices, and even hepatocellular carcinoma. Meanwhile, for patients with severe hepatitis, hepatic encephalopathy, upper gastrointestinal bleeding, infection, hepatorenal syndrome and other complications can be induced, and some patients may also be life-threatening. In some patients, symptoms can be controlled with active treatment, but they need lifelong follow-up and cannot be cured. There are also some who are severely ill and have a poor prognosis. It is recommended that patients with thirty years of viral hepatitis C follow the doctor’s instructions for systematic treatment in a timely manner, and actively cooperate with the doctor to do their own care, so as not to delay the condition.