The treatment of high blood lipids in patients with self-exempted liver is categorized into general treatment, drug treatment and surgical treatment. General treatment refers to the adjustment of life and diet; drug treatment includes statins, fibrates, niacin and its derivatives, etc.; surgical treatment includes partial ileocolic resection and portal vein shunt. 1. General treatment: diet should be light, avoid greasy food, eat more vegetables and fruits; moderate exercise, reduce weight; quit smoking, limit alcohol, salt control and so on. 2. Medication: statins such as Rosuvastatin and Simvastatin. Biotics such as fenofibrate and gemfibrozil. Niacin and its derivatives, such as acipimox. 3. Surgery: For patients with aggravated condition or unsatisfactory effect of long-term drug treatment, partial ileal resection and portal vein shunt can be considered. For patients with self-exempted liver and high blood lipid, it is recommended to go to the hospital in time, and the doctor will choose the appropriate treatment plan according to the situation. Drugs should be used under the guidance of a doctor.