In patients in their fifties, there may be somatic pathologies or psychological factors that lead to insomnia. For example, patients with hypertension, diabetes mellitus, hyperlipidemia, and hyperhomocysteinemia are prone to atherosclerosis, resulting in inadequate blood supply to the brain. Acute coronary syndromes such as angina pectoris or myocardial infarction may also occur, and the patient’s sleep quality may be affected by the presence of somatic discomfort, leading to insomnia. Insomnia is also likely to occur if there is an emotional disorder, such as when the patient is more irritable, tense, fearful and restless or has a low mood, lack of motivation, or depression.