Nose bleeding can not be stopped may be due to the formation of dry nasal mucous membrane ulcers, blood vessels brittle and other reasons, may also be due to hemophilia and other coagulation disorders and tumors and other causes. 1. dry nasal mucosa formed ulcers: due to the climate and other reasons caused by the nasal mucosa dry mucous membrane elasticity itself will be reduced, coupled with repeated external stimuli to make the local formation of ulcers, resulting in the local can not be healed more than bleeding. 2. bleeding blood vessels brittle: nasal mucosa blood vessels or capillaries brittle, digging, trauma, etc. will lead to nasal blood vessel rupture bleeding, bleeding is more difficult to stop. Nose bleeding can not be stopped, it is recommended to go to the hospital in a timely manner, by a professional physician on the patient’s condition of electrocoagulation, filling expansion sponge to stop bleeding. 3. Coagulation disorders: including angiogenic hemophilia, giant platelet disorder, liver cirrhosis, etc. These diseases will lead to coagulation dysfunction and bleeding after nosebleed. 4. Nasal cavity and sinus tumors: including hemangioma and nasopharyngeal carcinoma, etc., whose bleeding is also difficult to stop after rupture of the tumor, and it is recommended to go to the hospital in time. The occurrence of such symptoms should be treated urgently and actively seek medical treatment to identify the causes and then standardize the diagnosis and treatment.