Abnormalities of bilirubin metabolism generally include prehepatic jaundice, hepatocellular jaundice, and posthepatic jaundice, which require different medications and surgical treatments depending on the disease. 1. Pre-hepatic jaundice: i.e. hemolytic jaundice, which will cause short-term destruction of a large number of blood cells, exceeding the liver’s ability to convert and excrete bilirubin, and then inducing the elevation of total bilirubin and indirect bilirubin, and requires active treatment of the primary pathology, for example, taking medicines to promote the conversion of bilirubin, such as Phenobarbital tablets. 2. Hepatocellular jaundice: for example, drug hepatitis, viral hepatitis and alcoholic hepatitis may cause liver injury, which may lead to the elevation of direct bilirubin and indirect bilirubin at the same time, and it is necessary to receive liver-protecting and anti-yellowing treatment, for example, oral adenosylmethionine butanedisulfonate. 3. Post-hepatic jaundice: generally it is mainly obstructive jaundice and bile duct diseases, such as tumors and stone diseases, which need surgical or interventional treatment. In addition, the application of the above drugs has a certain degree of risk, need to get the guidance of specialists, not blindly use their own drugs.