Aspirin is an anti-platelet aggregation drug, widely used in the treatment and prevention of atherosclerosis and venous thromboembolism. The mechanism of action is the irreversible inhibition of platelet cyclooxygenase activity, which inhibits platelet activation, aggregation and release, thus achieving the anti-platelet effect. Alternative to aspirin are: first, hydroclopidogrel, tigretol, also another pathway to anti-platelet aggregation, mainly by inhibiting platelet surface adenosine diphosphate receptors and act, second, cilostazol, selective inhibition of phosphodiesterase activity, reduce phosphorylase degradation, increase platelet and blood phosphate adenosine content, so that anti-platelet effect occurs. Third, tirofiban, which is a mid-membrane relief that inhibits platelet aggregation, thus prolonging bleeding time and inhibiting thrombosis, which is a commonly used antiplatelet agent and can replace aspirin.