Leprosy phobia is a clinical diagnosis of disease phobia. Leprosy terror is a neurological disorder characterized by a strong fear of leprosy disease, the cause of which is unknown, and some patients have a timid, shy, dependent, introverted personality. Some patients have been subjected to inappropriate health education or trauma as a trigger. What are the examination methods of leprosy terror? 1, Mycobacterium leprae examination Take an active skin lesion tissue fluid print for antacid staining, TT is mostly negative, LL is mostly positive. Mainly from the skin and mucous membranes to take material, if necessary, can be lymph node puncture to check the bacteria. Skin examination: select active, skin lesions and disinfect the skin. Wear sterile gloves, use the left thumb and index finger to pinch and lift the patient’s skin, so that the local skin becomes white, and then the right hand holds the knife to cut a 5-mm-long, 3-mm-deep incision, scrape the tissue fluid with the knife blade, apply it to the carrier film, fix the antacid stain, and microscopy. Incision cotton ball paste pressure, the number of sampling sites as needed. 2, histopathological examination The main manifestation is epithelial-like cell infiltration around the small blood vessels and nerves in the dermis, antacid staining is often not found antacid bacillus; LL manifestation contains foam cells (i.e. leprosy cells) granuloma in the dermis, antacid staining shows a large number of foam cells within the bacillus leprae, because it does not invade the superficial layer of the dermis, so there is a non-infiltrative band between the epidermis and the dermis. Leprosy bacteriocin test: Leprosy bacteriocin test is used to determine the body’s delayed metabolic reaction to Mycobacterium leprae, TT is mostly strong positive, while LL is mostly negative. It is a simple method to determine the body’s resistance to Mycobacterium leprae, which can partially reflect the strength of the body’s cellular immune response to Mycobacterium leprae and the presence or absence of. The types of leprosy bacteriocin are crude leprosy bacteriocin, pure bacillus leprosy bacteriocin and pure protein leprosy bacteriocin, and the current common one is crude leprosy bacteriocin (also called complete leprosy bacteriocin). Test method and result judgment: Inject 0.1 ml of crude leprosy bacteriocin into the flexor side of the forearm intradermally to form a white bulge of about 6-8 mm in diameter, and observe the reaction results later. Early reaction: 48 hours after injection to observe and judge the results, the injection site with infiltrative erythema greater than 20 mm in diameter is a strong positive (thirty), 15 to 20 mm is a moderate positive (twenty), 10 to 15 mm is a weak positive (+), 5 to 10 mm is suspicious (±), 5 mm or less or no reaction is negative (-); late reaction: 21 days after injection to observe and judge the results, the injection site Red infiltrative nodules with rupture are strongly positive (XXX), nodule infiltration diameter greater than 5 mm is moderately positive, nodule infiltration diameter 3 to 5 mm is weakly positive (+), mild nodule infiltration or below 3 mm is suspicious (±), no local reaction is negative (-). 3, physical examination To systematically and comprehensively examine the skin, nerves and lymph nodes of the whole body under natural light. When examining the nerves, attention should be paid to both changes in the peripheral nerve trunk and changes in sensory and motor functions. The peripheral nerve trunk examination generally pays attention to the greater auricular nerve, ulnar nerve and peroneal nerve, others such as the supraorbital nerve, anterior cervical nerve, supraclavicular nerve, middle nerve, radial nerve, superficial peroneal nerve, posterior tibial nerve and the dermatomal nerve around and beneath the skin lesion. The examination should pay attention to its stiffness, thickness, nodularity, presence of pustules, and pressure pain. Nerve function examination, which is the determination of the nerve not slightly involved, is divided into subjective and objective examination methods.