Chronic moderate inflammation of the gastric sinus mucosa with mild enteritis is usually seen in atrophic gastritis, and the treatment includes conservative treatment and surgical treatment. 1. Chronic moderate inflammation of gastric sinus mucosa with mild enterocolitis belongs to a kind of pathological change, which is usually caused by infection and autoimmune factors, which can lead to the damage of gastric sinus mucosa, and enterocolitis will occur when the damaged epithelial cells of gastric sinus mucosa are replaced by intestinal epithelial cells. The phenomenon of intestinalization belongs to a kind of precancerous lesion. If the pathological and histological examination reveals that no cancer has occurred, it is recommended to use antibiotics such as clarithromycin capsule, gastric mucous membrane protection agents such as bismuth pectin, acid inhibitors such as omeprazole and gastric stimulating drugs such as domperidone tablets for conservative treatment. 2. If the results of pathological and histological examination suggest that cancer cells have appeared in the patient’s lesion, it is considered that cancer has already occurred. In this case, doctors will usually suggest surgery, and commonly used surgical methods include palliative surgery for gastric cancer and major gastrectomy, etc. In the meantime, patients should be treated according to immunohistochemical examination. In the meantime, a reasonable radiotherapy program should be formulated according to the immunohistochemistry test results. It is recommended that patients should go to regular hospitals for consultation and follow the doctor’s instructions according to the relevant examination results.