Solid nodule in the upper lobe of the left lung with pleural pulling is mostly considered as lung cancer, tuberculosis, inflammation and other diseases, and the treatment includes medication and surgery, etc. The use of medication should be in accordance with the doctor’s prescription. 1. Lung cancer: the nodule will be accompanied by signs of lobulation and burr, etc. Surgery can be chosen for radical resection, combined with radiotherapy and chemotherapy, and chemotherapeutic drugs such as cisplatin can be used. 2. Tuberculosis: the appearance of tuberculosis ball will have corresponding symptoms, and most of them will be accompanied by satellite foci around, which need regular anti-tuberculosis treatment, such as the use of isoniazid, rifampicin and so on. 3. Inflammation: some inflammatory diseases will have relevant symptoms during recovery, and need regular application of anti-inflammatory drugs for control, such as ceftriaxone. Solid nodule pleural pulling in the upper lobe of the left lung can also be seen in other diseases, and it is recommended that the patient seek medical treatment in time to avoid delaying the condition.