If you have a fever after drinking, of course you can take antipyretic drugs, as long as the fever is heavy or the accompanying symptoms are obvious, you can take antipyretic drugs for symptomatic treatment. But whether or not to take antipyretic drugs must depend on the degree of fever, and drinking has little to do with it, eating antipyretic drugs will not cause the symptoms of drinking to increase significantly. The cause of the fever after drinking should be clarified. It is possible that the fever is caused by a cold or other infection before or after drinking, so in addition to taking antipyretic drugs, you should also look for the cause and then treat the cause. The main drugs that cannot be taken after drinking are those that may have a disulfiram-like reaction, such as cephalosporin antibiotics, which cannot be taken and should only be taken after the alcohol has been completely metabolized in the body.