The treatments for anal fissure include general treatment, medication, and in serious cases, surgery. 1. General treatment: pay attention to anal hygiene and reasonable diet, don’t eat greasy and spicy stimulating food, eat more fresh vegetables and fruits, and keep the bowels smooth to prevent dryness, constipation and difficulty in defecation. 2. Medication: Apply nitroglycerin ointment to relieve edema and pain, and use lactulose and other medications to loosen and lubricate the stool and keep it smooth. Patients with inflammatory bowel disease can apply dexamethasone, mesalazine, salazosulfapyridine and other drugs for anti-inflammatory. It can also be combined with the use of 1:5000 potassium permanganate solution for sitz bath. 3. Surgery: For particularly severe anal fissure, surgery can be considered, such as anal fissure resection, partial resection of the internal sphincter of the anal canal, and so on, and the appropriate surgical method can be chosen according to the condition. In the course of treatment, follow the doctor’s instructions, use medication reasonably, and consult the doctor regularly for review.