Coma of cerebral infarction is also relatively common, and it is common in large cerebral infarction or infarction of brain stem. In addition to comprehensive treatment such as active antithrombotic, dehydration and cranial pressure lowering or internal environment stabilization: First, we should monitor vital signs, perform 24-hour cardiac monitoring, monitor his respiration, pulse rate, blood pressure and oxygen saturation, and give oxygen therapy when oxygen saturation is lower than 95% or blood gas analysis indicates hypoxia. Secondly, patients in coma with cerebral infarction should be given gastric tube nasal feeding as soon as possible to prevent aspiration pneumonia and to avoid loss of fluid or lack of nutrition due to insufficient dietary intake. Third, the position of the body should be taken in the lateral position, if in the supine or flat position, the head should be to the side to prevent the tongue root back or secretions blocking the airway, and often change position to prevent bedsores. Turn and pat the back regularly to prevent the occurrence of pneumonia. Attention should be paid to the placement of the limbs on both sides. Fourth, when the condition of patients with cerebral infarction is stable, rehabilitation should be carried out as soon as possible to reduce the functional deficits caused by stroke and improve the quality of life of patients.