Septic meningitis in children, referred to as chemoencephalitis, is caused by various bacterial infections. This kind of children usually start the disease more rapidly, a few days before the disease, that is, within a few days may have a history of respiratory tract, gastrointestinal tract pre-infection, the main manifestations of fever, mental fatigue, or even lethargy, impaired consciousness, and then have a headache, vomiting. Elderly children have headache, projectile vomiting, infants and young children, especially small infants, he will not say headache, often manifested as restlessness, irritability, refusal of milk, refusal to eat, and even screaming. There are also a small number of children will have convulsions, accompanied by lethargy, lethargy, coma, or even deep coma performance. Septic meningitis, and some children will appear hemiplegia and other manifestations, which is a typical clinical manifestation of septic meningitis. However, it should be reminded that not all cases of purulent meningitis have typical manifestations. In the case of small infants and children, especially those younger than three months of age, the clinical manifestations are often not typical. The child often may or may not have a fever or even a temperature. There are also some patients who do not show significant intracranial hypertension. For example, in intracranial hypertension, older children will complain of headache and projectile vomiting, while younger infants tend to show milk spillage, spitting up, and bulging fontanel with increased tension, and that’s where it varies. Another atypical symptom is convulsions, which are very atypical in small infants, and may be very acute, with a very inconspicuous expression, blinking or chewing-like movements, or rowing-like movements, or pedaling-like movements of the feet like a bicycle. These children do not have the typical convulsive episodes that older children have, so parents may not always be able to recognize septic meningitis in their children.