Semen is all sludge blood may be related to seminal vesiculitis, seminal vesicle stones and other diseases. It is recommended to treat the cause of the disease, and common methods include medication and surgery. 1. Seminal vesiculitis: Since the vesicourethral excretory ducts and the vas deferens converge to form the ejaculatory ducts, it is easy to lead to the infection of the seminal vesicles. Seminal vesiculitis leads to localized mucosal breakage and bleeding of the seminal vesicles, and the situation of semen mixed with bruises will occur during ejaculation. It is recommended to use tetracycline, erythromycin, clarithromycin and so on to carry out anti-infection treatment. 2. Seminal vesicle stones: for asymptomatic seminal vesicle stones, can not be treated; such as stones combined with infection or stone friction caused by the seminal vesicle bleeding can also lead to hematospermia, the need for anti-infective treatment, commonly used drugs such as levofloxacin, cephalosporin, and so on. If necessary, you need to have a vesicoscopic surgery to remove the stone. There are many reasons why the semen is all sloshed, it is recommended to check as soon as possible, and follow the doctor’s instructions, step-by-step treatment.