Creatinase correctly should refer to the enzyme creatine kinase, which can lead to high levels when muscle tissues are strained, such as by strenuous exercise, massages, muscle strains, muscle crush injuries, etc. High levels of creatine kinase are also seen in cardiac muscle damage. The dangers of elevated creatine kinase, particularly high creatine kinase within the bloodstream, may cause damage to the kidneys, and may also cause walking disorders, respiratory failure, and so on. Creatine kinase is a normal substance that exists in human muscle tissue and has no side effects of its own. There is a large amount of creatine kinase in muscle tissue, and when muscle tissue is damaged or strained, such as by strenuous exercise, massages, muscle strains, and muscle crush injuries, creatine kinase is released into the bloodstream, resulting in elevated creatine kinase. Creatine kinase is an important indicator of cardiac enzymes, and high creatine kinase is also seen in cardiac muscle damage. Creatine kinase is found mainly in skeletal muscle, heart muscle and brain tissue. Particularly high levels of creatine kinase within the bloodstream may cause damage to the kidneys, leading to severe renal insufficiency; if it affects the skeletal muscles, there may be impediments to or difficulties in walking; if it affects the respiratory muscles, respiratory failure may occur in severe cases. When creatine kinase is on the high side, you should consult a doctor in time and use medication for treatment under the doctor’s guidance.