Fever reducer suppositories will be absorbed and take effect in about 0.5~2 hours, and the effect is relatively fast. Acetaminophen is the main ingredient in fever suppositories, and some products may contain diclofenac sodium and ibuprofen. Like acetaminophen, diclofenac sodium, ibuprofen drugs work faster, fever suppositories are absorbed into the body through rectal administration, and can relieve the symptoms of fever and generalized muscle pain. If the symptoms of fever persist after the use of antipyretic suppositories, the medication can be repeated every 4 to 6 hours as prescribed by the doctor. If the patient’s fever symptoms have not been relieved, it is necessary to go to the hospital in time for examination, and then according to the cause of fever treatment. Antipyretic suppositories belong to non-steroidal anti-inflammatory drugs, in the use of the process may have adverse reactions, such as nausea, vomiting and other symptoms, but also on the liver, especially after the use of too much will cause transaminases rise, not beneficial to the body. Although antipyretic suppositories are common antipyretic drugs, pregnant women should avoid using them so as not to affect the fetus, and in addition, like the elderly should avoid using them in large doses to prevent increasing the risk of thromboembolism.