According to the nine divisions of the abdomen, the gallbladder is in the right upper abdomen, physically located at the junction of the right rib cage and the right midclavicular line, adjacent to the liver anteriorly, and is located in the gallbladder fossa posteriorly and inferiorly to the liver. The gallbladder is usually not palpable on palpation. The main function of the gallbladder is to store concentrated bile, and it also secretes a small amount of bile. When the gallbladder duct is blocked, bile secretion is impeded and bile sludges up, making cholecystitis easy to form when infected by bacteria and other pathogens. The main components of bile include cholesterol, bile salts and bile acids. When a high-fat diet and lack of exercise are present, gallstones are very likely to form, and acute cholecystitis is formed when combined with infection. Since the gallbladder is located in the right upper abdomen, cholecystitis and gallstones usually present with pain in the right upper abdomen and radiating pain to the right shoulder, accompanied by nausea, vomiting, fever and other clinical manifestations. If the patient has the above symptoms, it is recommended to go to the regular hospital in time for examination, to clarify the cause of the disease in time, and active treatment. Do not delay the condition and miss the best treatment time.