Effects of Clopidogrel Hydrogen Sulfate Tablets

Clopidogrel is mainly used clinically to inhibit platelet aggregation, belongs to ADP receptor antagonist, applicable to recent ischemic stroke, acute myocardial infarction, peripheral arterial disease, and also can reduce the occurrence of arterial occlusion, relatively more common adverse reactions are bleeding, gastrointestinal reactions, rash, some patients may also appear leukopenia, generally after 3-7 days of administration can reach steady state Platelet aggregation and bleeding time gradually return to baseline levels 5 days after discontinuation, plasma concentration is proportional to the dose used, this drug is mainly metabolized by the liver and has a half-life of about 8 hours. For patients with acute coronary syndrome episodes, a combination with aspirin, called dual anti, or double antiplatelet, is recommended. For patients with renal insufficiency, no adjustment of the dose used is required.