If you utilize progesterone to induce menstruation, it is usually given for 3 days and then stopped for 3-7 days before menstruation occurs. Under normal circumstances, after the intramuscular injection of progesterone due to the progesterone itself is an oil, so it will cause local pain, absorption will be relatively difficult, it is recommended that after the injection in the local area can be used to promote the absorption of the drug with hot compresses to reduce the local pain. In addition, if after the intramuscular injection of progesterone, the eighth or ninth day after stopping the drug still did not come to menstruation, we must rule out the possibility of pregnancy, you can use early pregnancy test paper to do the test. If there is no pregnancy, it is recommended to go to the hospital as soon as possible to do the appropriate examination, to exclude the possibility of ovarian dysfunction, because ovarian dysfunction is irreversible, even if the progesterone clinically will not come to menstruation.