Weakness of legs after holmium ureter laser surgery may be related to the effect of anesthesia medication, intraoperative posture, and blood clots in the lower limbs, so it is necessary to clarify the cause before adjusting the treatment. 1. The effect of anesthesia drugs: Holmium ureter laser surgery usually adopts general anesthesia, due to the effect of anesthesia drugs, weakness of legs may appear for a period of time after the surgery. With the metabolism of the drugs, the symptoms will subside slowly. 2. Intraoperative position: In order to facilitate surgical operation, the patient usually adopts the lithotomy position during the operation. The patient lies flat on the operating table, and the lower limbs are lifted up and forked to fully expose the perineal area. As the patient is under anesthesia, the muscles of the whole body are flaccid, if the position is not appropriate or the operation time is long, it may induce the symptoms of weakness of both legs. 3. Lower limb thrombosis: the patient is in the amputation position, the lower limbs need to be lifted up, and the popliteal fossa and other areas may be compressed. If the patient has hyperlipidemia and high blood viscosity, it may induce venous thrombosis in the lower limbs, which may also induce the symptoms of weakness in the legs. To summarize, if there is any discomfort, consult a doctor in time.