Commonly used clinical markers of hepatitis B virus include hepatitis B five, hepatitis B DNA, etc. Hepatitis B DNA reflects the amount of hepatitis B virus in the body and is also a marker of infectiousness, and it can also be used as an indicator for antiviral efficacy evaluation. In addition to hepatitis B DNA, the five indicators of hepatitis B, namely hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B E antigen, hepatitis B E antibody and hepatitis B core antibody. If the hepatitis B surface antigen is positive, it indicates hepatitis B virus infection and further liver function, hepatitis B DNA and liver ultrasound are needed to assess the condition. A positive hepatitis B E antigen, commonly known as a major triplet, indicates active hepatitis B virus replication, while a positive hepatitis B E antibody, commonly known as a minor triplet, is a sign of diminished virus replication. If the hepatitis B surface antibody is positive, it indicates that there are protective antibodies and such people will not get hepatitis B. The purpose of the five tests is to determine whether or not you have been infected with hepatitis B, and whether or not you have protective antibodies.