Thickening of blood vessels can be seen as a physiologic change, but some patients may have pathologic changes, such as varicose veins. The thickening of blood vessels can be physiologic, for example, blood vessels will expand in the summer when the weather is hot, especially the blood vessels on the surface of the body can appear obvious thickening, which is a physiologic change, will not have a serious effect on the human body, and does not need special treatment. The thickening of blood vessels in some patients is a pathologic change, such as varicose veins. Varicose veins are associated with elevated vascular pressure. Partial obstruction of venous reflux can lead to increased pressure in the veins, resulting in thickening of the blood vessels. The thickening of arterial vessels is mostly atheromatous dilatation, which is mostly caused by pathologic changes, such as atherosclerosis and aortitis. Thickening of blood vessels should understand the specific causes and severity of the disease, under the guidance of the doctor to develop a specific treatment program.