Slightly elevated total and indirect bilirubin suggests the possibility of hepatobiliary diseases, hematologic disorders, other diseases, and physiologic etiology. 1. Hepatobiliary diseases: e.g. hepatocellular jaundice, acute hepatic necrosis, acute jaundice hepatitis, chronic active hepatitis, cirrhosis, etc. 2. Blood diseases: such as hemolytic anemia, acute hemolytic transfusion reaction, hypersplenism, etc. 3. Other diseases: such as severe burns, sepsis, malaria, etc. 4. Physiological etiology: e.g. pregnancy, strenuous exercise, hunger strike, oral contraceptives, etc. The total bilirubin value is obtained by adding the direct bilirubin and indirect bilirubin values. A slight increase in both values is considered to be due to physiological causes, while a significant increase suggests that the patient may be suffering from a disease. Therefore, if the total bilirubin and indirect bilirubin are found to be elevated, it is necessary to undergo a series of tests to determine the cause of the disease and to treat it in a timely manner.