Slurred speech in a 50-year-old patient may be caused by neurological factors, i.e. the presence of brain infarction, brain hemorrhage, or the presence of a small tumor compressing the nerve in charge of speech in the brain, resulting in inflexible movement of the tongue or oral muscles, causing the patient to speak with a slurred speech. If the patient has degenerative brain nerve degeneration, the patient may also have symptoms of lisp, such as Alzheimer’s disease, or the presence of neuroinflammation, demyelination lesions, etc., may cause the patient’s nervous system in charge of speech can not function normally, and thus appear lisp. For patients with slurred speech at the age of 50, hearing is usually not considered because the patient could speak normally in the past, which means that the patient’s speech function has been developed. After the age of 50, the patient may have hearing loss, but because the patient’s speech habits have been formed, even though the patient cannot hear the sound after speaking, the articulation habits have been formed and the problem of lisp does not occur.