Big toe weakness can not tiptoe if it is caused by the lumbar spine compression of the nerve, you can first conservative treatment, conservative ineffective choice of surgical treatment. If it is caused by peroneal nerve compression, it can be treated by surgery. Herniated lumbar disc compresses the nerves that innervate the lower limbs, and when the compression is severe, the symptom of tiptoe weakness of the big toe will appear. Conservative treatment can be chosen first, such as hot compresses, baking electricity, acupuncture and other physiotherapy, and oral anti-inflammatory and analgesic drugs, such as nimesulide, diclofenac sodium, as well as neurotrophic drugs, such as methylcobalamin, adenosine cobalamin, etc. After treatment, if there is still no significant improvement, surgery is the first option. If there is still no significant improvement after treatment, it can also be treated by surgery, such as open spinal canal decompression bone graft fusion internal fixation surgery. If the problem is caused by peripheral nerve compression, such as peroneal nerve entrapment syndrome, there may be weakness in the big toe and the inability to stand on tiptoe. Surgery to decompress the peroneal nerve can relieve the symptoms. If the weakness of the big toe is caused by a ruptured tendon in the dorsum of the foot, it can be treated with surgical tendon repair and external immobilization in a plaster cast. If the symptoms of weakness of big toe can not tiptoe, it is recommended that the patient go to the hospital for medical examination, to clarify the cause of the disease, and to carry out regular treatment.