Intestinal melanosis is a non-inflammatory bowel disease characterized by dark pigmentation of the intestinal mucosa and is a reversible intestinal mucosal lesion that may be associated with the use of diaphoretic drugs containing anthraquinone-based chemicals. The use of anthraquinone-containing drugs may cause hyperpigmentation of the colonic mucosa, which can be seen as punctate leopard pattern-like changes in the colonic mucosa on colonoscopy, and is usually not malignant. During the onset of intestinal melanosis, abdominal pain, abdominal distension, difficulty in defecation, loss of appetite and other manifestations, need to be based on the results of the examination of the treatment as prescribed by the doctor. During the recovery period, the diet should be light and easy to digest, avoiding the intake of too stimulating and greasy food, so as not to aggravate the condition. Patients with intestinal melanosis need to stop taking laxatives in time, go to a regular hospital, consult a professional doctor, and cooperate with the doctor to complete the relevant examinations, so as to avoid blind treatment.