Sinus rhythm t-wave changes are divided into physiological and pathological causes, physiological causes do not require treatment, and pathological causes require treatment. Sinus rhythm is a normal heart rate, and the change of T-wave in ECG is affected by emotion, position, late night, heart disease and other factors; therefore, whether sinus rhythm t-wave needs treatment or not needs to be determined on a case-by-case basis. 1. Physiological reasons: If the sinus t-wave changes are caused by emotions, body position, late night, high stress, etc., no treatment is needed, regular checkups and maintaining a healthy lifestyle are sufficient. 2. Pathological reasons: if it is due to myocardial ischemia, coronary heart disease, heart valve disease and other organic heart disease, it is necessary to check the myocardial enzymes under the guidance of the doctor, cardiac ultrasound or coronary angiography to make a definitive diagnosis, if necessary, to take aspirin, atorvastatin, isosorbide nitrate, metoprolol tablets and other medications, and if necessary, the feasibility of percutaneous coronary interventional surgery. Sinus rhythm t-wave changes may also have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment or standardized treatment.