Plateau reaction is related to air temperature and pressure, but not only caused by air temperature and pressure, but also related to oxygen concentration. In the plateau area, the oxygen concentration in the air is relatively low, the air pressure is also relatively low, the air temperature is low and the temperature difference between day and night is large. These climatic conditions of the plateau will make the alveolar oxygen partial pressure of people who are new to the plateau decrease, affecting the normal exchange of gases in the alveoli, which in turn causes the partial pressure of oxygen in the human body to decrease, and the tissues are in a state of hypoxia, resulting in a plateau reaction. People who live in the plains for a long time, the first time to the plateau area, by the influence of the plateau climate characteristics are more prone to plateau reaction. It is recommended that people who need to go to the plateau area to do the relevant training in advance, prepare oxygen cylinders and drugs to cope with plateau reaction, once the body appears to be unwell to consult a doctor in a timely manner.