12-year-old girl vulvovaginitis if it is non-specific vulvovaginitis can be potassium permanganate sitz bath, fungal caused by the use of antifungal ointment external coating, trichomonas caused by oral metronidazole. 1. Non-specific vulvovaginitis: Inflammation of the vulvar skin or mucous membrane caused by friction of underwear or irritation of urine. Need to find and actively eliminate the cause, improve local hygiene, keep the vulva clean, dry, reduce friction. At the same time, can be used externally potassium permanganate sitz bath. 2. Vulvovaginitis caused by fungus: mostly caused by Candida infection, anti-fungal ointment can be used, such as compound clotrimazole cream. Compound clotrimazole cream has antifungal effect, adverse reactions include rash, itching. Allergic to this product is prohibited. 3. Vulvovaginitis caused by trichomonas: oral metronidazole tablets can be taken as prescribed by the doctor, this product has the effect of trichomonas. This product has the effect of inactivating trichomonas. This product is forbidden to those who have active central nervous system diseases and blood diseases. Adverse reactions include nausea, vomiting, abdominal cramps, and loss of appetite. The presence of vulvovaginitis in a 12-year-old girl should be regulated under the guidance of a doctor, and the medication should be used rationally.